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Updated: Aug 13, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 15, 2010
[Eye involvement in AIDS-related Kaposi sarcoma]
M Corti1, R Solari, L de Carolis
1Unidades 10-11 y Servicio de Oftalmología, Hospital de Infecciosas, F. J. Muñiz Buenos Aires, Argentina. marcelocorti@ciudad.com.ar
Background:
The study evaluates the incidence of ocular compromise in the Kaposi's sarcoma associated with AIDS.
Methods:
We revised the clinical histories of HIV seropositives patients seen in the ophthalmology department from January, 1994 to December, 1998. All patients were examined by direct visually and dilated fundus examination with the use of either a direct or an indirect ophthalmoscope.
Results:
In 6,552 patients, ocular Kaposi's sarcoma was diagnosed in 17 (0.25%), predominantly in male sex (88.23%). The lesions predominated in eyelids, and the inferior has been the most affected. In only one female, the ocular compromise was the first neoplastic manifestation.
Conclusions:
The ocular compromise in the Kaposi's sarcoma is an alternative to be considered in AIDS patients with previous or simultaneous cutaneous or visceral involvement. Due to the few clinical signs of these lesions, a thorough ocular study is recommended in these patients.
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