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Effect of inositol on bulimia nervosa and binge eating
D Gelber1, J Levine, R H Belmaker
1Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, P.O. Box 4600, Beersheva, Israel.
Objectives:
This study aimed to determine whether inositol has therapeutic value in patients with bulimia nervosa and binge eating.
Method:
A double-blind crossover trial using 18 g inositol versus placebo was performed in 12 patients for 6 weeks in each arm.
Results:
Inositol was significantly better than placebo on the Global Clinical Impression, the Visual Analogue Scale, and the Eating Disorders Inventory.
Discussion:
Inositol is as therapeutic in patients with bulimia nervosa and binge eating as it is in patients with depression and panic and obsessive-compulsive disorders. This increases its parallelism with serotonin selective reuptake inhibitors.