Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evidence-based surgery in chronic rhinosinusitis.

V J Lund1

  • 1Institute of Laryngology & Otology, University College London, UK. v.lund@ucl.ac.uk

Acta Oto-Laryngologica
|March 29, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and psychometric validation of the Chronic Rhinosinusitis Control Test.

Rhinology·2025
Same author

Indication for biologics in a real-world cohort of dupilumab treated chronic rhinosinusitis with nasal polyps patients according to international recommendations: evidence from the European CRS Outcome Registry (CHRINOSOR).

Rhinology·2025
Same author

Pocket guide: biologics in upper and lower airways in adults.

Rhinology·2025
Same author

Remission in chronic rhinosinusitis with nasal polyps (CRSwNP).

Rhinology·2025
Same author

Nasal endoscopy score thresholds to trigger consideration of chronic rhinosinusitis treatment escalation and implications for disease control.

Rhinology·2024
Same author

EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP.

Rhinology·2024

Evidence-based medicine is challenging for surgical procedures. This review examines the scientific validity of studies on surgery for chronic rhinosinusitis within this framework.

Area of Science:

  • Otolaryngology
  • Evidence-Based Medicine
  • Surgical Research

Background:

  • The rise of evidence-based medicine (EBM) necessitates rigorous evaluation of clinical practices.
  • Randomized controlled trials (RCTs) are the gold standard in EBM, but are difficult to implement for surgical interventions.
  • Chronic rhinosinusitis (CRS) is a common condition where surgical treatment is frequently employed.

Purpose of the Study:

  • To review the existing literature on surgical interventions for chronic rhinosinusitis.
  • To critically assess the methodological quality and validity of studies evaluating CRS surgery.
  • To evaluate the evidence for CRS surgery within the principles of evidence-based medicine.

Main Methods:

  • Systematic literature search for studies on CRS surgery.

Related Experiment Videos

  • Appraisal of study designs, including randomization, blinding, and placebo controls.
  • Assessment of evidence quality and strength for surgical outcomes in CRS.

    • Main Results:

    • Significant challenges exist in conducting high-quality RCTs for CRS surgery.
    • Much of the current evidence relies on observational studies with inherent limitations.
    • The validity of evidence supporting surgical benefits in CRS varies considerably.

    Conclusions:

    • High-level evidence for the efficacy of CRS surgery is often limited due to methodological constraints.
    • Further research employing robust methodologies is needed to strengthen the evidence base for CRS surgical treatments.
    • A critical appraisal of available evidence is essential for informed clinical decision-making in CRS management.