Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Faculty Mentor Development Intervention on Mentees' Subjective Career Success.

The chronicle of mentoring & coaching·2026
Same author

Impact of Mentors on Overall Faculty Experience and Reason for Leaving.

The chronicle of mentoring & coaching·2026
Same author

Effectiveness of a Structured Curriculum-Based Developmental Network Intervention.

The chronicle of mentoring & coaching·2026
Same author

Cross-Cultural Communication in Mentoring: Impact on Individual Growth.

The chronicle of mentoring & coaching·2026
Same author

Machine learning for predicting climate change impacts on <i>Pseudopithomyces chartarum</i> spore counts: a risk indicator of facial eczema.

New Zealand veterinary journal·2025
Same author

Cardiac dysfunction in transfusion-dependent β-thalassaemia: Insights into apolipoprotein E genotypes and iron metrics in a north Indian cohort.

British journal of haematology·2025

Related Experiment Video

Updated: Jul 18, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

Chronic hepatitis--changing trends.

A Sood1, P Singh, V Midha

  • 1Unit of Gastroenterology, Department of Medicine, Dayanand Medical College and Hospital, Ludhiana-141 001.

The Journal of the Association of Physicians of India
|March 29, 2001
PubMed
Summary

Hepatitis diagnosis and classification require identifying the cause, whether viral, autoimmune, or metabolic. Etiology is crucial for prognosis and effective treatment, especially with advancements in understanding viral genotypes and new therapies.

Area of Science:

  • Hepatology
  • Virology
  • Immunology

Background:

  • Hepatitis presents with diverse clinical features based on viral etiology (Hepatitis A-G).
  • Accurate hepatitis diagnosis necessitates etiological identification, including viral, autoimmune, and metabolic causes.
  • Histological classification alone is insufficient; etiological factors are paramount for chronic hepatitis.

Purpose of the Study:

  • To highlight the importance of etiological classification in hepatitis diagnosis and management.
  • To discuss the evolution of prognostic indices for interferon therapy in chronic viral hepatitis.
  • To review recent updates in autoimmune hepatitis classification and treatment.

Main Methods:

  • Review of clinical expressions, courses, and consequences of different viral hepatitis types.

More Related Videos

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

Related Experiment Videos

Last Updated: Jul 18, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

  • Analysis of diagnostic approaches emphasizing etiological factors over histology alone.
  • Examination of advancements in understanding prognostic factors for interferon therapy.
  • Assessment of recent changes in autoimmune hepatitis definition and therapeutic agents.

    • Main Results:

    • Etiological specificity is essential for complete hepatitis diagnosis and effective management.
    • Prognostic indices for interferon therapy have improved with insights into viral genotypes, ferritin, iron, viral load, and histology.
    • Newer immunosuppressive agents show promising results for autoimmune hepatitis.

    Conclusions:

    • Etiological diagnosis is fundamental for accurate hepatitis classification and patient management.
    • Understanding viral and host factors significantly enhances treatment strategies for chronic viral hepatitis.
    • Advances in autoimmune hepatitis diagnosis and therapy offer improved patient outcomes.