Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An update on obsessive-compulsive disorder.

M A Jenike1

  • 1Harvard Medical School, MA, USA. jenike@mediaone.net

Bulletin of the Menninger Clinic
|April 3, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2013
Same author

Genome-wide association study of obsessive-compulsive disorder.

Molecular psychiatry·2012
Same author

A magnetic resonance imaging study of regional cortical volumes following stereotactic anterior cingulotomy.

CNS spectrums·2006
Same author

Improvement in severe self-mutilation following limbic leucotomy: a series of 5 consecutive cases.

The Journal of clinical psychiatry·2002
Same author

The Skin Picking Impact Scale (SPIS): scale development and psychometric analyses.

Psychosomatics·2001
Same author

Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder.

Biological psychiatry·2001
Same journal

Identifying factors associated with sleep disturbance among adults seeking outpatient psychiatric services for anxiety and related disorders.

Bulletin of the Menninger Clinic·2026
Same journal

From unplanned attempts to planned deaths: A comparative analysis of suicidal behavior in rural Türkiye.

Bulletin of the Menninger Clinic·2026
Same journal

Toward a double bind theory of borderline personality disorder.

Bulletin of the Menninger Clinic·2026
Same journal

An evaluation of factor structure, measurement invariance, and psychometric properties of the Psychache Scale.

Bulletin of the Menninger Clinic·2026
Same journal

Psychiatric and behavioral symptoms after pediatric herpes simplex virus type 1 encephalitis: An exploratory case series.

Bulletin of the Menninger Clinic·2026
Same journal

Object relations moderate the relationship between emotion regulation and quality of life among psychiatric inpatients: A brief report.

Bulletin of the Menninger Clinic·2026
See all related articles

Obsessive-compulsive disorder (OCD) impacts 3% globally. Effective treatments include behavior therapy and medication, with neurosurgery offering options for severe cases, though some patients remain refractory.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Global Health

Background:

  • Obsessive-compulsive disorder (OCD) affects nearly 3% of the global population, representing a significant worldwide health concern.
  • Advances in neuroimaging have enhanced understanding of OCD's biological underpinnings and involved brain circuits.

Purpose of the Study:

  • To review current understanding and treatment of obsessive-compulsive disorder (OCD).
  • To highlight effective therapies and explore options for treatment-refractory patients.

Main Methods:

  • Review of recent developments in neuroimaging techniques.
  • Analysis of controlled data on behavior therapy (exposure and response prevention) and pharmacotherapy.
  • Evaluation of neurosurgical and neurostimulation approaches.

Related Experiment Videos

Main Results:

  • Exposure and response prevention, alongside specific medications, are the most effective evidence-based treatments for OCD.
  • Neurosurgical and neurostimulation interventions show potential for severely impaired individuals, though controversial.
  • A subset of OCD patients does not respond to current treatments.

Conclusions:

  • Current research supports behavior therapy and medication as primary OCD treatments.
  • Further investigation into neurosurgical and neurostimulation techniques is warranted for refractory cases.
  • Future research should prioritize understanding and treating treatment-resistant OCD populations.