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Neonatal intestinal perforation in a developing country.

L B Chirdan1, E A Ameh

  • 1Paediatric Surgery Unit, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. ssrs.njsr@skannet.com

Annals of Tropical Paediatrics
|April 4, 2001
PubMed
Summary

Neonatal intestinal perforation in Nigeria is a serious condition, with a high mortality rate of 59% among 14 cases. Early diagnosis and surgical intervention are critical for improving outcomes in these vulnerable infants.

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Area of Science:

  • Pediatric Surgery
  • Neonatal Care
  • Gastrointestinal Surgery

Background:

  • Intestinal perforation in neonates is a critical surgical emergency.
  • Associated congenital anomalies and iatrogenic causes contribute to the condition.
  • Limited data exists on the outcomes of neonatal intestinal perforation in developing countries.

Purpose of the Study:

  • To analyze the causes, management, and outcomes of neonatal intestinal perforation.
  • To identify risk factors associated with mortality in affected neonates.
  • To provide insights into surgical strategies for intestinal perforation in a resource-limited setting.

Main Methods:

  • Retrospective case series of 14 neonates treated for intestinal perforation.
  • Data collection included patient demographics, clinical presentation, surgical procedures, and outcomes.

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  • Statistical analysis focused on identifying factors influencing mortality.

    • Main Results:

    • The study included 14 neonates with a median age of 9 days and weight of 2.65 kg.
    • Common causes included anorectal malformation, Hirschsprung's disease, and ruptured exomphalos.
    • Seven perforations were in the small bowel and seven in the colorectum, with an overall mortality rate of 59%.

    Conclusions:

    • Neonatal intestinal perforation carries a high mortality rate, particularly in resource-limited settings.
    • Prompt surgical intervention, including laparotomy and appropriate repair, is essential.
    • Further research is needed to improve survival rates through enhanced neonatal care and surgical techniques.