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Published on: October 22, 2013
Campylobacter Enteritis and the Guillain-Barré Syndrome
1Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 4th Floor Gates Building, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA. nachamki@mail.med.upenn.edu
Abstract:
Campylobacter jejuni is one of the most common causes of bacterial gastroenteritis in the United States and worldwide with approximately 2.4 million infections per year in the United States. A now clearly recognized sequelae following Campylobacter infection is the Guillain-Barré syndrome, an acute immune-mediated attack on the peripheral nervous system. How Campylobacter induces Guillain-Barré syndrome is the subject of intense investigation, and this article discusses some of the recent advances in our understanding of the clinical, epidemiologic, and pathogenic features of the disease.
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