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In vitro cultivation and characterization of axenic amastigotes of Leishmania

N Gupta1, N Goyal, A K Rastogi

  • 1Division of Biochemistry, Central Drug Research Institute, -226001, Lucknow, India

Trends in Parasitology
|April 5, 2001
PubMed

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Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...