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Chicken Nkx6.1 expression at advanced stages of development identifies distinct brain nuclei derived from the basal

E Puelles1, J L Rubenstein, L Puelles

  • 1Department of Morphological Sciences, Faculty of Medicine, University of Murcia, E30100, Murcia, Spain.

Mechanisms of Development
|April 5, 2001
PubMed

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...