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Updated: Aug 10, 2026

Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
[Changes in immune state in patients with duodenal ulcer disease]
Abstract:
There were examined 73 patients with giant ulcer (GU) of the duodenum and 62--with the smaller size ulcer of the duodenum. In majority of patients essential disorders of immune state were revealed: reduction of the T-lymphocytes quantity, disbalance of their subpopulation composition, the rise of the circulating immune complexes level, activization of autoimmune reactions. In patients with duodenal GU immune disorders were more pronounced, than in the presence of the smaller size duodenal ulcer. Maximum changes of the immune status were observed in patients with complications of duodenal GU--perforation, penetration, haemorrhage.
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