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Collagen membranes: a review.

P Bunyaratavej1, H L Wang

  • 1Department of Periodontics/Prevention/Geriatrics, School of Dentistry, University of Michigan, Ann Arbor 48109-1078, USA.

Journal of Periodontology
|April 6, 2001
PubMed
Summary
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Collagen membranes are effective in guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures, offering comparable results to non-absorbable options. Further long-term studies are needed to confirm their benefits in periodontal and peri-implant defects.

Area of Science:

  • Biomaterials Science
  • Periodontology
  • Dental Regenerative Medicine

Background:

  • Collagen materials exhibit excellent biocompatibility and promote wound healing, making them valuable in medicine and dentistry.
  • Collagen membranes are absorbable yet prevent epithelial downgrowth, aiding guided tissue regeneration (GTR).
  • Their use in conjunction with grafting materials shows promise for furcation defects.

Purpose of the Study:

  • To review the rationale and literature supporting collagen membrane use in periodontal and peri-implant regenerative therapies.
  • To discuss the properties that make collagen attractive for regenerative applications.
  • To explore cross-linking techniques that modify collagen degradation rates.

Main Methods:

  • Review of in vitro and in vivo studies on collagen membranes in GTR, guided bone regeneration (GBR), and root coverage.

Related Experiment Videos

  • Comparison of collagen membranes with non-absorbable membranes (e.g., ePTFE) and connective tissue grafts.
  • Analysis of clinical outcomes including probing depth reduction, clinical attachment gain, and bone fill.

    • Main Results:

    • Collagen membranes demonstrate comparable efficacy to non-absorbable membranes in GTR procedures.
    • Successful application of collagen in GBR and root coverage procedures has been reported.
    • Combined use with grafting material may enhance outcomes for furcation defects but not intrabony defects.

    Conclusions:

    • Collagen membranes are a viable option for various periodontal and peri-implant regenerative procedures.
    • While promising, long-term clinical trials are essential to fully ascertain the benefits of collagen membranes.
    • Cross-linking techniques are crucial for controlling the degradation rate and optimizing the performance of collagen membranes.