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Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae

Y Kamimura1, Y S Tak, A Sugino

  • 1Division of Microbial Genetics, National Institute of Genetics, Osaka University, Osaka 565-0871 Japan.

The EMBO Journal
|April 11, 2001
PubMed
Summary

The novel protein Sld3 forms a complex with Cdc45, crucial for DNA replication initiation. This Sld3-Cdc45 complex is essential for recruiting replication machinery to origins, enabling DNA unwinding.

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