Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Angiocentric lymphomas (lymphomatous vasculitis).

Y Natkunam1, R A Warnke

  • 1Department of Pathology, Stanford University Medical Center, CA 94305, USA. ynatkunam@yahoo.com

Seminars in Diagnostic Pathology
|April 12, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.

Oncogene·2017
Same author

The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment.

Current hematologic malignancy reports·2015
Same author

Syk-induced phosphatidylinositol-3-kinase activation in Epstein-Barr virus posttransplant lymphoproliferative disorder.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2013
Same author

Expression of the CD2AP adaptor molecule in normal, reactive and neoplastic human tissue.

Pathologica·2012
Same author

Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2011
Same author

Light-chain-restricted germinal centres in reactive lymphadenitis: report of eight cases.

Histopathology·2008
Same journal

Update on the molecular pathology of the distinctive giant cell, fibro-osseous and bone forming lesions of the jaws.

Seminars in diagnostic pathology·2026
Same journal

Update on the molecular pathology and classification of odontogenic cysts and tumours.

Seminars in diagnostic pathology·2026
Same journal

MDM2 gene amplification in surgical pathology: biology, diagnostic utility, and clinical relevance in the modern era.

Seminars in diagnostic pathology·2026
Same journal

When three negatives equal a positive: Molecular updates of triple-negative breast carcinomas with favorable prognoses.

Seminars in diagnostic pathology·2026
Same journal

Old school, new insight: Revisiting histomorphology in the modern era of prostate cancer risk stratification.

Seminars in diagnostic pathology·2026
Same journal

Recent advances in genetic predisposition to primary testicular tumors.

Seminars in diagnostic pathology·2026
See all related articles

Angiocentric lymphomas, a diverse group of blood cancers, are characterized by their unique growth pattern around blood vessels. This article reviews their classification, diagnosis, and clinical features.

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Angiocentric lymphomas are a group of hematolymphoid malignancies defined by their angiocentric or perivascular growth pattern.
  • This category encompasses T-cell, B-cell, and natural killer (NK)-cell derived lymphomas with diverse clinicopathologic features and prognoses.

Purpose of the Study:

  • To outline the salient clinicopathologic features of natural killer (NK) and NK-like T-cell lymphomas.
  • To address the diagnostic challenges associated with these lymphomas.
  • To present an integrated approach for their diagnosis.

Main Methods:

  • Review of clinicopathologic features.
  • Immunophenotypic and molecular characterization.
  • Analysis of diagnostic difficulties and integrated diagnostic strategies.

Related Experiment Videos

Main Results:

  • Angiocentric lymphomas are heterogeneous, including T-, B-, and NK-cell derived types.
  • Initial classification focused on NK and NK-like T-cell lymphomas with angiocentric growth.
  • Reclassification based on improved characterization reveals shared features with other lymphomas and leukemias.

Conclusions:

  • Angiocentric lymphomas represent a complex spectrum of malignancies.
  • Accurate diagnosis requires an integrated approach considering morphology, immunophenotype, and molecular data.
  • Distinguishing these from other lymphoid neoplasms is crucial for appropriate patient management.