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Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging
Published on: November 20, 2018
Cyclotron production of 67Ga(III) with a tandem natGe-natZn target
1National Accelerator Centre, Faure, South Africa. naidoo@nac.ac.za
Abstract:
Production of 67Ga(III) at the National Accelerator Centre is by proton bombardment of a natZn target, and uses 15-20 h of cyclotron beam time per production. A study was undertaken to use a tandem natGe-natZn target to produce the same amount of 67Ga, but using less beam time (7-8 h). 67Ga(III) was separated from the tandem target material by a method based on acid dissolution of the target and chromatography on an organic polymer resin (Amberchrom CG-71cd) containing no ion exchange groups. The separated 67Ga(III) has high radionuclidic purity and complies with the British and US Pharmacopoeia requirements for chemical purity.
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