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Pulmonary imaging and function in the common cold.

T Puhakka1, M Lavonius, M Varpula

  • 1Department of Pediatrics, Turku University Hospital, Finland.

Scandinavian Journal of Infectious Diseases
|April 17, 2001
PubMed
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The common cold primarily affects the upper respiratory tract, with this study finding no significant lower respiratory tract issues in healthy young adults. This research confirms that lower respiratory tract abnormalities are rare in common cold cases.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Epidemiology

Background:

  • The common cold is typically viewed as an upper respiratory tract infection.
  • Limited data exists on the lower respiratory tract's involvement during common cold infections.

Purpose of the Study:

  • To investigate the lower respiratory tract in otherwise healthy young adults experiencing the common cold.
  • To determine the prevalence of lower respiratory tract abnormalities during a common cold episode.

Main Methods:

  • Recruited 76 healthy young adults with common cold symptoms.
  • Diagnosed viral infections, with Rhinovirus being the most common.
  • Utilized chest radiography (CR), high-resolution computerized tomography (HRCT), and pulmonary function tests (PFTs) with bronchodilator challenges.

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  • Conducted clinical examinations and symptom tracking via diary cards over 20 days.

    • Main Results:

    • Viral infections were confirmed in 74% of subjects, with Rhinovirus in 55%.
    • No pulmonary changes were detected via CR or HRCT.
    • PFTs showed no significant bronchodilator response.
    • Mean cough duration was 8.4 days, and sputum production was 5.9 days.
    • All patients recovered clinically within 21 days without antimicrobial treatment.

    Conclusions:

    • The common cold in young, healthy adults is predominantly an upper respiratory tract infection.
    • Clinically significant lower respiratory tract abnormalities are uncommon during the common cold.
    • Findings support the classification of the common cold as an upper respiratory illness.