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Related Concept Videos

Pneumonia I: Introduction01:29

Pneumonia I: Introduction

2
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
2
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

1.4K
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.4K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

1.3K
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.3K
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

4.1K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
4.1K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

4.5K
The pathophysiology of pneumonia involves the following steps:
4.5K
Pneumonia IV: Management01:28

Pneumonia IV: Management

1.1K
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
1.1K

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Related Experiment Video

Updated: Apr 18, 2026

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
08:04

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

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Fatal varicella pneumonia.

J Sander1, A Serck-Hanssen, J C Ulstrup

  • 1Department of Infectious Diseases, the Department of Pathology and the Bacteriological/Virological Laboratory, Ullevål Hospital, Oslo, Norway.

Scandinavian Journal of Infectious Diseases
|January 22, 2015
PubMed
Summary

A fatal case of varicella pneumonia occurred in a 37-year-old woman. Post-mortem examination confirmed extensive lung, skin, and liver involvement by varicella virus, with no identifiable predisposing factors.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Virology

Background:

  • Varicella-zoster virus (VZV) typically causes a mild childhood illness.
  • Severe VZV infections, including pneumonia, can occur, particularly in immunocompromised individuals or adults.

Purpose of the Study:

  • To describe a rare case of fatal varicella pneumonia in an otherwise healthy adult.
  • To highlight the potential severity of VZV infection.

Main Methods:

  • Case report of a 37-year-old woman with fatal varicella pneumonia.
  • Clinical diagnosis supported by post-mortem examination.
  • Viral isolation of VZV from clinical samples.

Main Results:

  • Extensive pulmonary, cutaneous, and hepatic involvement by VZV.

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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
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  • VZV confirmed via isolation from vesicular fluid and post-mortem lung fluid.
  • No predisposing factors identified for the severe outcome.

    • Conclusions:

    • Varicella pneumonia can be fatal in adults, even without apparent risk factors.
    • Highlights the importance of considering severe VZV complications in adult presentations.