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Risk factors of persistent diarrhea in children below five years of age

A S Karim1, S Akhter, M A Rahman

  • 1Department of Pediatric Nutrition and Gastroenterology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh. karimb@bangla.net

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|April 18, 2001
PubMed

Insights

Persistent diarrhea in Bangladeshi children is linked to malnutrition, unsafe water, and improper antibiotic use. Exclusive breastfeeding for four months is crucial for prevention.

Area of Science:

  • Pediatrics
  • Public Health
  • Infectious Diseases

Background:

  • Persistent diarrhea is a major cause of mortality, morbidity, and malnutrition in children in developing nations.
  • Understanding associated risk factors is critical for effective intervention strategies.

Purpose of the Study:

  • To identify host and environmental risk factors for persistent diarrhea in Bangladeshi children under five years of age.

Main Methods:

  • A prospective analytic case-control study was conducted.
  • Fifty children with persistent diarrhea and 50 age- and sex-matched controls with acute diarrhea were recruited.
  • The study was set in a tertiary hospital in Dhaka, Bangladesh.

Main Results:

  • Grade III malnutrition, irrational antibiotic use, unsafe drinking water, and lack of exclusive breastfeeding were significantly associated with persistent diarrhea.
  • Logistic analysis identified irrational antibiotic use during acute diarrhea and lack of exclusive breastfeeding as independent risk factors.
  • Most affected children (82%) were under two years old.

Conclusions:

  • Improving nutritional status is vital for preventing persistent diarrhea.
  • Promoting exclusive breastfeeding for the first four months and discouraging irrational antibiotic use are key preventive measures.
  • Ensuring access to safe drinking water is essential for reducing the incidence of persistent diarrhea.
Abstract

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