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Related Experiment Videos

Combined pre- and post-surgical bupivacaine wound infiltrations decrease opioid requirements after knee ligament

N N Butterfield1, S K Schwarz, C R Ries

  • 1Clinical Pharmacology Research Organization, Department of Pharmacology & Therapeutics, The University of British Columbia, Vancouver, Canada.

Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie
|April 18, 2001
PubMed
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Selective local anesthetic infiltration before and after surgery significantly reduced opioid use and improved recovery time following arthroscopic cruciate ligament reconstruction (ACLR). This technique offers superior pain management compared to standard intra-articular injections alone.

Area of Science:

  • Orthopedic Surgery
  • Anesthesiology
  • Pain Management

Background:

  • Postoperative pain management is crucial for recovery after arthroscopic cruciate ligament reconstruction (ACLR).
  • Standard pain control often involves intra-articular injections, but efficacy can be limited.

Purpose of the Study:

  • To evaluate the effectiveness of combined pre- and post-surgical local anesthetic infiltration versus standard intra-articular injection for reducing opioid consumption after ACLR.
  • To compare patient recovery and adverse events between the two pain management strategies.

Main Methods:

  • A double-blind, randomized controlled trial involving 23 patients undergoing elective ACLR.
  • The treatment group received bupivacaine infiltrations at surgical sites and intra-articularly before and after surgery.

Related Experiment Videos

  • The control group received saline infiltrations, with both groups receiving a standard intra-articular injection post-surgery.

    • Main Results:

    • The treatment group required significantly less postoperative opioid medication (5.8 mg vs. 13.7 mg morphine equivalent, P = 0.008).
    • Patients receiving selective infiltrations were discharged approximately 30 minutes earlier (P = 0.046).
    • No adverse events were reported in the treatment group, unlike the control group.

    Conclusions:

    • Combined pre- and post-surgical selective wound infiltration with bupivacaine provides superior analgesia after ACLR.
    • This enhanced local anesthetic technique improves pain control and accelerates patient recovery.
    • The method is safe and effective, offering an advantage over standard intra-articular injections.