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Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine
D S Pardi1, E V Loftus, W J Tremaine
1Division of Gastroenterology and Hepatology, Mayo Clinic and Foundation, Rochester, Minnesota, USA. pardi.darrell@mayo.edu
Abstract:
Many patients with microscopic colitis will respond to antidiarrheal medications or to anti-inflammatory therapy with 5-aminosalicylates, although a few require corticosteroids. Some patients do not tolerate corticosteroid side effects, and a small subset are dependent on or refractory to corticosteroids. We report our experience with azathioprine and 6-mercaptopurine in patients with microscopic colitis.
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