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Molecular characterization of a rare hemoglobin variant: Hb-Hinsdale: beta139(H17)ASN-->Lys

V Degani1, D Leone, R Murtas

  • 1Laboratorio di Ematologia, Ospedale Infantile Regina Margherita, Università degli Studi, Torino, Italy.

Minerva Medica
|April 24, 2001
PubMed

The authors describe the characteristics of a rare hemoglobin mutant found in a young female. She carries the aminoacid replacement of Hb-Hinsdale:beta139(H17)ASN-->Lys, which was identified at molecular level. This case, clinically and hematologically symptomless, is identical, but genetically independent, to the cases first described in an American family.

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