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High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
Published on: June 21, 2011
Determination of the presampled MTF in computed tomography
1Department of Radiology, University of California, Davis, UC Davis Medical Center, Sacramento 95817, USA. jmboone@ucdavis.edu
Abstract:
A technique for measuring the presampled MTF in CT scanners is described. The technique uses a simple phantom consisting of approximately 0.050 mm aluminum foil sandwiched by flat plastic or tissue-equivalent slabs. The aluminum foil is slightly angled with respect to the reconstruction matrix, and CT images are acquired. The acquired CT image yields an angled slit image that can be used to synthesize the presampled line spread function (LSF). The presampled MTF is calculated from the presampled LSF. The technique is a direct extension of that proposed by Fujita et al. [IEEE Trans. Med. Imaging 11, 34-39 (1992)] for MTF calculation on digital radiography images. While the MTF in clinical CT scanners often reaches negligible amplitude below the Nyquist frequency, the technique is easy to implement, requires inexpensive materials, is robust to aliasing, and is more resilient to noise due to greater data averaging than conventional PSF-integration techniques. Use of the proposed technique is illustrated on a clinical multiple detector array scanner, and MTFs are shown for several common reconstruction kernels. It is likely that the proposed technique would be useful for all tomographic imaging systems, including single photon emission computed tomography, positron emission tomography, magnetic resonance imaging and ultrasound scanners.
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