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Updated: Jun 25, 2026
09:25
Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment
Published on: February 22, 2017
[Hydroa vacciniforme: dietary fish oil]
A B Modeste1, N Cordel, X Balguerie
1Clinique Dermatologique, Unité INSERM U519, Hôpital Charles Nicolle, CHU de Rouen.
Annales De Dermatologie Et De Venereologie
|April 25, 2001
Summary
Dietary fish oil effectively treated hydroa vacciniforme, a rare childhood skin condition. This treatment, rich in omega-3 fatty acids, reduced inflammation and lesions, offering a new therapeutic option for this photodermatosis.
Area of Science:
- Dermatology
- Photodermatology
- Nutritional Science
Background:
- Hydroa vacciniforme is a rare childhood photodermatosis with significant scarring potential.
- Current treatments for hydroa vacciniforme have variable efficacy.
- Dietary fish oil has been suggested as a potential therapeutic agent.
Observation:
- A 15-year-old female presented with typical hydroa vacciniforme lesions.
- Previous treatments including antimalarials and photoprotection were unsuccessful.
- Administration of dietary fish oil (Maxepa®) led to rapid lesion regression.
Findings:
- Dietary fish oil supplementation resulted in complete resolution of hydroa vacciniforme lesions within weeks.
- The therapeutic effect was observed despite seasonal challenges (summer).
- Treatment was interrupted due to side effects (fetid breath) but reintroduction also led to resolution.
Implications:
- Dietary fish oil, rich in omega-3 polyunsaturated fatty acids, may reduce inflammation in hydroa vacciniforme.
- This intervention could increase epidermal omega-3 fatty acids and decrease skin prostaglandins.
- Fish oil represents a promising, albeit potentially poorly tolerated, treatment for hydroa vacciniforme.
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