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Updated: Oct 8, 2026

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
Published on: August 16, 2019
Human immunoglobulin for diabetic amyotrophy--a promising prospect?
A E Courtney1, G V McDonnell, V H Patterson
1Department of Neurology, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, UK. aecourtney@doctors.org.uk
Abstract:
Diabetic neuropathies are universally recognised and cause significant morbidity. At present improving glycaemic control is the only recognised treatment. A man with type 2 diabetes presented with disabling asymmetric lower limb proximal neuropathy. Rapid clinical, functional, and electrical improvement followed treatment with intravenous immunoglobulin. The aetiology of diabetic amyotrophy remains controversial but there is evidence for an immune mediated process and this case suggests a role for immunoglobulin in the management of this debilitating condition.
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