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Presumed Eales' disease with neurologic involvement: report of three cases
J Biswas1, R Raghavendran, G Pinakin
1Medical Research Foundation, Chennai, India. mrf@sankaranethralaya.org
Purpose:
To report three cases of presumed Eales' disease with neurologic lesions.
Methods:
Case reports, systemic and neurologic evaluation, and magnetic resonance imaging.
Results:
All three patients were young men who had seizures in the past; two had migrainous headache. Magnetic resonance imaging showed putaminal infarct in two cases and edema in the white matter of temporal cortex was noticed in one case. Clinical features in all these patients were suggestive of Eales' disease.
Conclusion:
Ischemic infarction of the brain can be seen in clinically suspected cases of Eales' disease.
Insights
This study reports three cases of Eales' disease presenting with neurologic lesions, including brain infarction and edema. These findings suggest that ischemic brain infarction can occur in patients suspected of having Eales' disease.
Area of Science:
- Neurology
- Ophthalmology
- Radiology
Background:
- Eales' disease is a rare condition characterized by inflammation of retinal vessels.
- Neurologic involvement in Eales' disease is uncommon but has been reported.
Observation:
- Three young male patients with presumed Eales' disease presented with neurologic symptoms.
- Two patients reported a history of seizures, and one experienced migrainous headaches.
Findings:
- Magnetic resonance imaging (MRI) revealed putaminal infarcts in two patients.
- White matter edema in the temporal cortex was observed in one patient.
- Clinical presentations were consistent with Eales' disease.
Implications:
- Brain infarction may be a manifestation of Eales' disease.
- Neurologic evaluation and MRI are crucial for diagnosing Eales' disease with CNS involvement.
- This highlights the importance of considering neurologic complications in Eales' disease management.