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Updated: Aug 18, 2026

Blood Collection from the American Horseshoe Crab, Limulus Polyphemus
Published on: October 13, 2008
[Poisoning from eating horseshoe crab and its prevention and treatment]
Abstract:
During the past three years on investigating and studying the poisoning of eating Horseshoe crab, it has been discovered that the major cause of the poisoning on eating Horseshoe crab in south region along the seacoast of China was taking tetrodotoxin from Carcinoscorpius rotundicauda by mistake; the symptoms of some others from eating Horseshoe crab were the result of allergic reactions from eating Tachypleus tridentatuscause, similar to the reactions from eating shrimp or crab, and which could be cured with chlorpheniramine. The effective prevention measures are not eating Horseshoe crab, especially the young ones. The size of young Carcinoscorpius rotundicauda is similar to the size of the nonpoisonous Tachypleus tridentatuscause. It is very easy to be confused and easy to eat by mistake. The treatment of the poisoning from eating Horseshoe crab is similar to the treatment of tetrodotoxin by removing the toxins from body.
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