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Noonan syndrome: a case with recurrent keloid formation
A T Güleç1, A Karaduman, D Seçkin
1Department of Dermatology, Baskent Universitesi Tip Fakültesi, Dermatoloji Anabilim Dali, 12. sokak, No 7/6, Bahçelievler 06490, Ankara, Turkey.
Cutis
|April 28, 2001
Summary
This case report details a 6-year-old boy with ulerythema ophryogenes and keratosis pilaris atrophicans faciei. These rare skin conditions were associated with characteristic features of Noonan syndrome.
Area of Science:
- Dermatology
- Genetics
- Pediatrics
Background:
- Ulerythema ophryogenes (UO) and keratosis pilaris atrophicans faciei (KPAF) are rare follicular keratoses.
- Noonan syndrome is a genetic disorder with diverse clinical manifestations.
Observation:
- A 6-year-old boy presented with erythema and horny, follicular papules on eyebrows and arms.
- The patient exhibited dysmorphic facial features, congenital heart disease, pectus excavatum, and cubitus valgus.
Findings:
- Diagnosis of ulerythema ophryogenes and keratosis pilaris atrophicans faciei was established.
- The patient displayed multiple characteristic features consistent with Noonan syndrome.
- A tendency for keloid formation was also noted.
Implications:
- This case highlights the co-occurrence of specific dermatological conditions with Noonan syndrome.
- Early recognition of these combined features may aid in timely diagnosis and management of Noonan syndrome.
- Further research into the genetic links between these conditions is warranted.