Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The evolving role of prostate brachytherapy.

D C Beyer1

  • 1Arizona Oncology Services, 8994 E. Desert Cove Avenue, Suite 100, Scottsdale 85260. dbeyer@azoncology.com

Cancer Control : Journal of the Moffitt Cancer Center
|April 28, 2001
PubMed
Summary

Prostate brachytherapy offers durable disease control for localized prostate cancer, with most recurrences occurring within five years. Ideal candidates have low-risk factors, while advanced cases may benefit from combination therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapeutic Strategies for Localized Prostate Cancer II: Perineal Prostatectomy, X-Rays, Protons, Neutrons, and Combination Brachytherapy.

Reviews in urology·2006
Same author

Prostate brachytherapy: comparison of dose distribution with different 125I source designs.

Radiology·2001
Same author

Pretreatment nomogram for predicting freedom from recurrence after permanent prostate brachytherapy in prostate cancer.

Urology·2001
Same author

Real-time optimized intraoperative dosimetry for prostate brachytherapy: a pilot study.

International journal of radiation oncology, biology, physics·2000
Same author

Failure free survival following brachytherapy alone for prostate cancer: comparison with external beam radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2000
Same author

Staging evaluation for patients with adenocarcinoma of the prostate. American College of Radiology. ACR Appropriateness Criteria.

Radiology·2000

Area of Science:

  • Oncology
  • Radiation Oncology
  • Urologic Oncology

Background:

  • Prostate brachytherapy use has increased due to large studies with long-term results.
  • This approach is a viable option for localized prostate cancer management.

Purpose of the Study:

  • To review the historical use and current outcomes of prostate brachytherapy.
  • To summarize implant techniques, risk stratification, and combination therapy effects.

Main Methods:

  • Historical review of brachytherapy for prostate cancer.
  • Summary of implant techniques and patient risk stratification.
  • Review of combination therapies for specific patient groups.

Main Results:

  • 12-year follow-up shows no failures after 10 years; 75% of recurrences within 5 years.
  • Low-risk patients (PSA ≤10, Gleason ≤7, low stage) have favorable outcomes.
  • Advanced disease may require brachytherapy with external-beam radiation therapy (EBRT).
  • Complications are primarily urinary.

Conclusions:

  • Brachytherapy provides durable disease control for localized prostate cancer.
  • Few failures occur after 5 years, with no recurrence after 10 years.
  • Improved pathologic tools could enhance patient selection for brachytherapy.

Related Experiment Videos