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Anterior sacral meningocele in a patient with Marfan syndrome

D Rigante1, G Segni

  • 1Department of Pediatrics, Università Cattolica Sacro Cuore, Rome, Italy. iclpe@rm.unicatt.it

Clinical Neuropathology
|May 1, 2001
PubMed

Insights

Anterior sacral meningocele is rarely linked to Marfan syndrome (MFS). This case highlights a rare association, presenting a large pelvic mass in an MFS patient diagnosed via MRI.

Area of Science:

  • Neuroscience
  • Genetics
  • Radiology

Background:

  • Marfan syndrome (MFS) is a genetic connective tissue disorder.
  • Dural ectasia is a common finding in MFS, affecting up to two-thirds of patients.
  • Anterior sacral meningocele (ASM) is a rare condition involving a cystic protrusion of the dura mater.

Observation:

  • A case study of an 18-year-old male with Marfan syndrome is presented.
  • MRI revealed a large cystic mass in the pelvic region, consistent with ASM.
  • The condition remained stable over a one-year follow-up period.

Findings:

  • This report describes a rare association between Marfan syndrome and anterior sacral meningocele.
  • The diagnosis was confirmed through detailed MRI morphological evaluation.
  • The observed ASM was a significant pelvic mass.

Implications:

  • This case expands the known spectrum of connective tissue abnormalities in Marfan syndrome.
  • It emphasizes the importance of considering ASM in MFS patients presenting with pelvic masses.
  • Further research may elucidate the underlying mechanisms connecting MFS and ASM.

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