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[Ebola fever: an emerging disease]
Summary
Ebola fever is a highly fatal disease caused by stable Ebola virus (EBO) subtypes. This review covers historical outbreaks, clinical presentation, diagnosis, patient care, and control strategies for managing Ebola virus infections.
Area of Science:
- Virology
- Epidemiology
- Infectious Diseases
Context:
- Ebola fever is a severe and often fatal viral hemorrhagic fever.
- The Filoviridae family virus has four distinct subtypes with varying pathogenicity.
- Understanding Ebola virus epidemiology is crucial for public health.
Purpose:
- To provide a comprehensive historical review of Ebola virus outbreaks and infections.
- To detail the clinical manifestations and laboratory diagnosis of Ebola virus disease.
- To discuss patient care, therapeutic options, and control measures for Ebola virus.
Summary:
- Presents a historical overview of Ebola virus epidemics, nosocomial, and laboratory infections.
- Details clinical symptoms and signs from 103 patients infected during the 1995 Kikwit outbreak.
- Covers laboratory diagnostics, patient care, antiviral drugs, immunotherapy, and infection control.
Impact:
- Informs on effective strategies for managing Ebola virus disease based on past experiences.
- Highlights the importance of barrier nursing, isolation, and contact tracing.
- Contributes to preparedness for future Ebola virus outbreaks globally.