Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Odorant exposure increases olfactory sensitivity: olfactory epithelium is implicated.

K K Yee1, C J Wysocki

  • 1Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104-3308, USA. karenyee@monell.org

Physiology & Behavior
|May 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Access of large and nonvolatile molecules to the vomeronasal organ of mammals during social and feeding behaviors.

Journal of chemical ecology·2013
Same author

Specific mesenchymal/epithelial induction of olfactory receptor, vomeronasal, and gonadotropin-releasing hormone (GnRH) neurons.

Developmental dynamics : an official publication of the American Association of Anatomists·2010
Same author

Ellipsometric investigation of quadratic electrooptic and electrostrictive effects with anodic niobium pentoxide films.

Applied optics·2010
Same author

Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics.

Neuroscience·2008
Same author

Analyses of volatile organic compounds from human skin.

The British journal of dermatology·2008
Same author

Left-handers have a lower prevalence of arthritis and ulcer.

Laterality·2005
Same journal

Apelin receptor antagonist (ML221) facilitates memory reconsolidation in novel object recognition task.

Physiology & behavior·2026
Same journal

Are humans adapted to the world they have developed?

Physiology & behavior·2026
Same journal

50-kHz ultrasonic vocalization subtypes emitted by female rats anticipating same-sex social interaction.

Physiology & behavior·2026
Same journal

Sex-dependent behavioral and prefrontal BDNF mRNA responses to extinction training and short-term citalopram after fear conditioning in rats.

Physiology & behavior·2026
Same journal

Social instability alters the topography of adolescent and adult social behavior and amygdala function.

Physiology & behavior·2026
Same journal

Mitochondrial remodeling in obesity: mechanistic links to impaired energy metabolism and therapeutic perspectives.

Physiology & behavior·2026
See all related articles

Odorant exposure increases sensitivity, and this effect persists even after olfactory nerve transection, suggesting peripheral olfactory system involvement. Sensitivity eventually returns to baseline levels over time.

Area of Science:

  • Neuroscience
  • Sensory Biology
  • Olfactory System Research

Background:

  • Exposure to odors can alter olfactory sensitivity through peripheral or central mechanisms.
  • The olfactory system's ability to adapt and recover from injury is a key area of research.

Purpose of the Study:

  • To investigate the role of the peripheral olfactory system in odorant-induced sensitization.
  • To examine the long-term effects of olfactory nerve damage on odor sensitivity.

Main Methods:

  • Odor thresholds were measured in mice before and after odorant exposure.
  • Mice underwent bilateral olfactory nerve transection (BNX) or sham surgery.
  • Olfactory function and sensitivity were assessed at various time points post-surgery.

Related Experiment Videos

Main Results:

  • Odorant exposure led to increased sensitivity to that specific odorant.
  • This heightened sensitivity persisted for at least 45-50 days after olfactory nerve transection.
  • Sensitivity returned to pre-exposure levels 121-203 days post-surgery.

Conclusions:

  • Findings provide evidence for peripheral olfactory system involvement in odorant sensitization.
  • The olfactory system demonstrates a capacity to maintain or regain sensitivity following injury.