Bioactive glass granules for regeneration of human periodontal defects
E S Rosenberg1, G K Fox, C Cohen
1New York University College of Dentistry, New York, New York, USA. erosen9468@aol.com
Purpose:
A comparative study which evaluated the effectiveness of bioactive glass granules of uniform size (300-335 microns) for the regenerative treatment of interproximal intrabony periodontal defects was conducted.
Materials And Methods:
Twelve pairs of advanced periodontal lesions in 12 patients (6 males and 6 females) were treated in a split-mouth design with open flap débridement in the control sites and open flap débridement with bioactive glass particles placed in the test sites.
Results:
At 6 months post-treatment, both treatment modalities demonstrated a gain in clinical attachment level (CAL), with the test sites having a significantly (p < .01) greater gain in CAL than the control sites. Reentry procedures were performed to assess the amount of hard tissue fill. The test sites demonstrated significantly (p < .001) more gain in hard tissue fill than the controls.
