Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microarray technology: the future of blood testing?

J Petrik1

  • 1Scottish National Blood Transfusion Service, NAT Reference Lab, LCMV, Royal (Dick) Veterinary College, Summerhall, Edinburgh EH9 10H. juraj.petrik@snbts.csa.scot.nhs.uk

Vox Sanguinis
|May 8, 2001
PubMed
Summary

Molecular biological techniques like nucleic acid amplification (NAT) and microarray technology are transforming blood screening. These advancements promise integrated platforms for comprehensive donor and donation testing, improving diagnostics for infectious diseases like hepatitis C virus (HCV).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatitis E virus in patients with decompensated chronic liver disease: a prospective UK/French study.

Alimentary pharmacology & therapeutics·2015
Same author

Evaluation of a potassium removal filter on irradiated red cells stored in SAGM.

Transfusion medicine (Oxford, England)·2015
Same author

Storage of apheresis platelet concentrates after manual replacement of >95% of plasma with PAS 5.

Vox sanguinis·2014
Same author

Hepatitis E virus in Scottish blood donors.

Vox sanguinis·2013
Same author

Novel approaches to antiviral and anticancer immunotherapy.

Acta virologica·2012
Same author

[Benefits of sentinel lymph node examination in early breast carcinoma].

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2011

Area of Science:

  • Molecular biology
  • Biotechnology
  • Medical diagnostics

Background:

  • Recent advancements in molecular biology have significantly impacted mass testing and diagnostics, particularly in blood screening.
  • Nucleic acid amplification techniques (NAT), often using polymerase chain reaction (PCR), are established in blood grouping and hepatitis C virus (HCV) screening.
  • Microarray technology, while often involving amplification, excels at simultaneous analysis of thousands of targets, leveraging genomic data.

Purpose of the Study:

  • To review the potential of microarray technology in revolutionizing blood testing.
  • To discuss the design of a blood-testing chip.
  • To explore various technologies applicable to integrated donor and donation testing.

Main Methods:

  • Review of current molecular biological techniques in diagnostics.

Related Experiment Videos

  • Analysis of microarray technology principles and applications.
  • Discussion of integrated platform concepts for blood screening.

    • Main Results:

    • Microarray technology offers a potential integrated platform for comprehensive donor and donation testing.
    • This technology could replace multiple individual assays, enhancing efficiency and scope.
    • The simultaneous analysis of thousands of analytes is a key benefit of microarrays.

    Conclusions:

    • Microarray technology holds significant promise for the future of blood testing and diagnostics.
    • An integrated platform using microarrays could revolutionize comprehensive donor and donation screening.
    • Further development in blood-testing chip design is crucial for realizing this potential.