Related Experiment Video
Updated: Aug 2, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Measuring complete diagnostic evaluation in colorectal cancer screening
R E Myers1, G Fishbein, T Hyslop
1Thomas Jefferson University, Department of Medicine, Philadelphia, PA 19107, USA.
Accurate measurement of complete diagnostic evaluation (CDE) use is crucial for colorectal cancer (CRC) screening. The combined internal chart audit and administrative data review method offers a highly sensitive and specific approach for tracking CDE performance.
Area of Science:
- Health Services Research
- Gastroenterology
- Public Health
Background:
- Complete diagnostic evaluation (CDE) is recommended following abnormal screening fecal occult blood tests for colorectal cancer (CRC).
- Accurate measurement of CDE utilization is essential for effective CRC screening programs.
Purpose of the Study:
- To compare the sensitivity and specificity of various methods for measuring CDE recommendation and performance.
- To identify the most accurate method for assessing CDE use in CRC screening.
Main Methods:
- The study evaluated five methods: external chart audit (ECA) only, internal chart audit (ICA) only, administrative data review (ADR) of electronic claims, ICA plus ADR, and ECA plus ADR (gold standard).
- Sensitivity and specificity of each method were assessed against the gold standard for both CDE recommendation and performance.
Main Results:
- For CDE recommendation, the ICA plus ADR method showed high sensitivity (0.901) and specificity (≥0.95).
- For CDE performance, ICA plus ADR demonstrated the highest sensitivity (0.965) with perfect specificity (1.0).
- External chart audit (ECA) only also showed high sensitivity for both recommendation (0.926) and performance (0.877).
Conclusions:
- The combination of internal chart audit and administrative data review (ICA-plus-ADR) is a highly sensitive and specific measure for assessing complete diagnostic evaluation use.
- This combined method should be considered for monitoring primary care physician follow-up of abnormal CRC screening results.
Related Concept Videos
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Serum Laboratory Studies, Stool Test, Breath Test
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures II: Colonoscopy
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...

