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A case-management program of medium intensity does not improve cardiovascular risk factor control in coronary artery
A Nordmann1, I Heilmbauer, T Walker
1Medical Outpatient Division, Department of Internal Medicine, University Hospital, Basel, Switzerland.
Insights
A medium-intensity case-management program for coronary artery disease did not significantly improve overall cardiovascular risk factors. However, it did lead to better cholesterol control at 18 months in patients after acute coronary events.
Area of Science:
- Cardiology
- Preventive Medicine
- Health Services Research
Background:
- Intensive case-management programs can reduce cardiovascular risk factors in coronary artery disease (CAD) secondary prevention.
- Less intensive approaches have not consistently demonstrated benefits.
- This study investigates a medium-intensity case-management program for CAD patients.
Purpose of the Study:
- To evaluate the effectiveness of a medium-intensity case-management program on cardiovascular risk factor control.
- To assess improvements in lipid values, blood pressure, glucose, BMI, and smoking cessation.
- To determine if this program offers a viable alternative to resource-intensive interventions.
Main Methods:
- A randomized trial involving 201 patients hospitalized for acute coronary events.
- Cluster randomization based on primary care physicians.
- Intervention group received 1-hour clinician counseling plus 3- and 6-month reminders; control group received usual care.
Main Results:
- No significant differences in lipid values, blood pressure, fasting blood glucose, BMI, or smoking rates at 9 or 18 months.
- A significantly higher proportion of patients in the intervention group achieved target cholesterol values at 18 months (48% vs. 27%, P=0.002).
- This cholesterol improvement was not observed at the 9-month follow-up.
Conclusions:
- A hospital-based, clinician-counseling-focused case-management program did not substantially improve overall cardiovascular risk factor control.
- The program showed a potential benefit in achieving target cholesterol levels at 18 months post-discharge.
- Further research may be needed to optimize case-management intensity and components for CAD secondary prevention.
Background:
Case-management programs for secondary prevention of coronary artery disease that utilize extensive resources can reduce cardiovascular risk factors, but less intensive approaches have failed to show benefits. This randomized trial evaluated whether a medium intensity case-management program improves risk factor control in patients with coronary artery disease.
Methods:
We assigned 201 consecutive patients hospitalized for acute coronary events in the intensive care unit of University Hospital, Basel, Switzerland, to either a risk factor case-management program (n = 99) or care as usual (n = 102) using the patients' primary care physicians as the unit of randomization (cluster randomization). The case-management program consisted of an hour of counseling by a clinician during hospitalization and two short reminders by phone and mail 3 and 6 months later. Treatment decisions were left to patients and their primary care physicians.
Results:
After 9 and 18 months of follow-up, there were no significant differences in lipid values, blood pressure control, fasting blood glucose, body-mass index, or number of smokers between the two groups. However, significantly more patients in the intervention group than in the care as usual group achieved target cholesterol values after 18 months (48% versus 27%, P = 0.002 and remained significant after Bonferroni-Holms correction) but not after 9 months of follow-up (31% versus 27%, P >0.2).
Conclusion:
This hospital-based case-management and outreach program, limited to counseling by a clinician, did not substantially improve cardiovascular risk factor control among patients hospitalized for coronary events.
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