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Updated: Jul 24, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Current concepts of bone healing
V J Mandracchia1, S C Nelson, E A Barp
1Foot and Ankle Clinics, Broadlawns Medical Center, Des Moines, Iowa, USA.
Abstract:
The intent of this article is to present the current understanding of fracture repair and offer investigative evidence to the use of exogenous growth factors enhancing fracture healing. The authors believe that exogenous growth factors have tremendous clinical applications and will continue to influence bone healing in the future. With the expanding knowledge of the intricate molecular and cellular biology of fracture repair being realized, surgeons will be able to enhance and ensure healing of surgical osteotomies, fractured bone ends, or delayed unions. This field of medicine is continuously growing and the possibilities seem endless.
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