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The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
Published on: August 21, 2012
Intravesical pressure and the TUR syndrome
1Department of Anaesthesia and Intensive Care, Stirling Royal Infirmary, Stirling FK8 2AU, UK. robgray@bigpond.com
Elevated intravesical pressure during transurethral prostate resection correlates with irrigating fluid absorption. Monitoring bladder pressure may aid in managing difficult procedures and training surgeons.
Area of Science:
- Urology
- Surgical Technology
Background:
- Transurethral prostate resection (TURP) involves irrigating the bladder.
- Absorption of irrigating fluid can lead to complications.
- Intravesical pressure during TURP is a potential factor in fluid absorption.
Purpose of the Study:
- To investigate the relationship between intravesical pressure and irrigating fluid absorption during TURP.
- To identify if elevated bladder pressure is a common pathway for fluid absorption.
Main Methods:
- Continuous intravesical pressure monitoring using a suprapubic catheter during 35 TURP procedures.
- Ethanol tagging of irrigating fluid and expired breath analysis to detect fluid absorption.
- Correlation analysis of pressure data with absorption and known risk factors.
Main Results:
- Patients absorbing irrigating fluid exhibited significantly higher mean intravesical pressure (19.1 mmHg) compared to non-absorbing patients (12.4 mmHg; p=0.00004).
- Higher peak intravesical pressures were observed in patients with fluid absorption.
- Operator experience and resectate mass correlated with prolonged pressure exposure.
Conclusions:
- Elevated intravesical pressure is a key factor associated with irrigating fluid absorption during TURP.
- Supranormal bladder pressure over time appears to be the common mechanism for fluid absorption.
- Bladder pressure monitoring could serve as a valuable feedback tool for surgical training and managing complex cases.
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