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Iron and hepatocellular carcinoma
1Clinique des Maladies du Foie, INSERM U522, Hôpital Pontchaillou, Rennes, France. yves.deugnier@univ-rennes1.fr
Journal of Gastroenterology and Hepatology
|May 15, 2001
Abstract:
The high prevalence of hepatocellular carcinoma (HCC) in genetic hemochromatosis (GH) and the association between increased body iron stores and occurrence of HCC in subjects with iron overload unrelated to GH, and the experimental evidence of a co-carcinogenic role of iron strongly support that iron is involved in the development of HCC.