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Detection of a coronary arterial thrombus by indium-111-oxine-labeled platelet scintigraphy
K Takahashi1, M Ohyanagi, J Tateishi
1First Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. keiko@hyo-med.ac.jp
Insights
A patient experienced chest pain after coronary artery stenting due to suspected thrombus formation. Indium-111 platelet scintigraphy confirmed thrombus accumulation at the stent site, highlighting a potential complication of coronary stenting.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Nuclear Cardiology
Background:
- Coronary artery disease management often involves percutaneous coronary intervention (PCI) with stenting.
- Myocardial infarction survivors require careful monitoring for post-procedural complications.
Observation:
- A 72-year-old male with myocardial infarction history presented with significant left anterior descending coronary artery stenosis.
- Following successful stenting, the patient developed acute chest pain within 12 hours.
Findings:
- Emergent coronary arteriography ruled out in-stent restenosis or new occlusions.
- Indium-111-oxine-labeled platelet scintigraphy revealed localized tracer accumulation at the stent site, suggesting coronary thrombus formation.
Implications:
- Early coronary thrombus formation is a potential complication after coronary stenting.
- Platelet scintigraphy can be a valuable tool in diagnosing stent-related thrombus when other methods are inconclusive.
- This finding underscores the importance of vigilant monitoring for thrombotic events post-stenting.
Abstract:
Coronary arteriography revealed significant left anterior descending coronary artery stenosis in a 72-year-old man with a history of myocardial infarction. Stenting of the stenotic vessel was performed. Twelve hours after stenting the patient complained of chest pain but emergent coronary arteriography did not show sign of any coronary arterial stenosis. Under suspicion of coronary thrombus formation, indium-111-oxine-labeled platelet scintigraphy was performed 5 days after stenting, and revealed accumulation of indium-111-oxine in the area corresponding to the stent implantation site.
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