Surgical treatment of epilepsy
Related Experiment Video
Updated: Oct 7, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
N Foldvary1, W E Bingaman, E Wyllie
1Department of Neurology, Section of Epilepsy and Sleep Disorders, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. foldvan@ccf.org
Abstract:
Approximately 30-40% of patients with focal epilepsy continue to have seizures despite appropriate medical therapy. Surgical treatments should be considered in this important subset of patients. Recent advances in neuroimaging technology have revolutionized the identification and evaluation of surgical candidates. The goal of the presurgical evaluation (video EEG monitoring, neuroimaging, and neuropsychological assessment) is to delineate the epileptogenic zone. Surgery is recommended when this has been adequately identified and the proposed procedure is expected to result in a high likelihood of seizure freedom and a low risk of neurologic and cognitive morbidity.
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