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Allergen avoidance: does it work?

A Woodcock1, A Custovic

  • 1Lung Function Unit, North West Lung Centre, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.

British Medical Bulletin
|May 22, 2001
PubMed
Summary
This summary is machine-generated.

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Allergen avoidance, a treatment for allergic disorders, has a long history. Environmental manipulation significantly improves asthma and allergy symptoms.

Area of Science:

  • Environmental Medicine
  • Allergology
  • History of Medicine

Background:

  • Allergen avoidance has been recognized as a therapeutic strategy for allergic disorders since the 16th century.
  • Early documented cases highlight physician Gerolamo Cardano's successful recommendation of feather bedding removal for asthma treatment.

Purpose of the Study:

  • To trace the historical evolution of allergen avoidance and environmental manipulation in managing allergic diseases.
  • To underscore the contemporary significance of environmental factors in the rising prevalence of asthma and allergies.

Main Methods:

  • Historical review of documented cases and controlled studies on allergen avoidance.
  • Analysis of early 20th-century environmental interventions for asthma, including dust-free rooms and climate chambers.

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Main Results:

  • Gerolamo Cardano reported a 'miraculous' remission of asthma symptoms in the 16th century following feather bedding removal.
  • Controlled studies in the early 20th century demonstrated asthma symptom improvement through environmental changes like dust reduction and climate-controlled chambers.

Conclusions:

  • Environmental manipulation has been a cornerstone in managing allergic disorders for centuries.
  • The historical success of allergen avoidance reinforces its critical role in addressing the current increase in asthma and allergic conditions.