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Multifocal subacute necrotizing encephalomyelopathy in a Simmental calf
I Desjardins1, G Fecteau, P Hélie
1Département de sciences cliniques, Faculté de médecine vétérinaire, Université de Montréal, C.P. 5000, Saint-Hyacinthe, Québec J2S 7C6.
Summary
Multifocal subacute necrotizing encephalomyelopathy causes hind limb weakness and ataxia in cattle. This neurological disorder is characterized by brainstem lesions, but its cause is currently unknown.
Area of Science:
- Veterinary Neurology
- Pathology
- Bovine Medicine
Background:
- Multifocal subacute necrotizing encephalomyelopathy (MSNE) is a neurological disease observed in Simmental and Simmental-cross cattle.
- Understanding the pathological basis of MSNE is crucial for cattle health management.
Observation:
- Clinical presentation includes ataxia and hind limb paresis.
- Gross pathological examination reveals bilaterally symmetrical, depressed to cavitated grey foci within the brainstem.
- The caudal olivary nucleus is consistently affected in all cases.
Findings:
- The observed lesions indicate a necrotizing process affecting specific brainstem nuclei.
- The symmetrical nature of the lesions suggests a potential toxic or metabolic etiology, though this is unconfirmed.
- Consistent involvement of the caudal olivary nucleus provides a key anatomical marker for the disease.
Implications:
- Further research is needed to elucidate the unknown etiology of MSNE.
- Identifying the cause could lead to preventative strategies and improved treatment for affected cattle.
- This condition poses a significant concern for Simmental cattle populations, impacting animal welfare and agricultural productivity.

