Is the determination of AHF activity feasible for individual cryoprecipitates?

A method is described in which the factor VIII (AHF) activity of 40 individual cryoprecipitates can be determined within 4 h. The reagents employed do not require plasma congenitally deficient in factor VIII. The preparation of cryoprecipitates with known biological activity should result in a more rational use of this type of factor VIII concentrate.