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Updated: Aug 1, 2026

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
Published on: June 21, 2017
Continuous wave ultrasonic tomography
H D Liang1, M Halliwell, P N Wells
1Centre for Physics and Engineering Research in Medicine, University of Bristol, Bristol General Hospital, Bristol BS1 6SY UK. haidong.liang@bristol.ac.uk
Abstract:
As an object rotates with respect to a stationary ultrasonic beam, the scattering centers within the object return echoes that are Doppler-shifted in frequency by amounts depending on the velocities of the individual scatterers. The scattering centers that lie on a line of constant cross-range all have the same effective velocity in the direction pointing toward the transducer; therefore, the backscattered echo amplitude at any particular frequency is the line integral of the scattered radiation at the cross-range corresponding to that frequency. The amplitudes of the returned signals at other frequencies give the line integrals for the scatterers at the corresponding cross-ranges. The amplitude as a function of frequency can be interpreted as a tomographic projection. A continuum of the projections at different positions is generated while the object is rotating. A tomographic reconstruction algorithm can produce an image of the distribution of scattering centers in the insonified object from these projections. A microscanner was developed to investigate the approach of using continuous wave (CW) ultrasound for cross-sectional imaging. The resolution is limited by the target size and the ultrasonic wavelength.
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