Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Action planning in a virtual context after prefrontal cortex damage.

T Zalla1, C Plassiart, B Pillon

  • 1CNRS, Institut des Sciences Cognitives, 67, Boulevard Pinel, 69675 Cedex, Bron, France.

Neuropsychologia
|May 23, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the brain basis of self-monitoring.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

The inter-relationships between cerebral visual impairment, autism and intellectual disability.

Neuroscience and biobehavioral reviews·2020
Same author

Enhanced recovery after surgery efficacy in an older patients and high-risk population affected by colorectal cancer: a more than 1000 patients experience.

Il Giornale di chirurgia·2020
Same author

Clinical and MRI Predictors of Conversion From Mild Behavioural Impairment to Dementia.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2020
Same author

Tailored anal block (TAB): a new anesthesia procedure for surgical treatment of hemorrhoids in an outpatient setting.

Techniques in coloproctology·2019
Same author

Aligning nomenclature for cognitive changes associated with anaesthesia and surgery with broader diagnostic classifications of non-surgical populations: a needed first step.

British journal of anaesthesia·2018
Same journal

Prevalence and modulation of rat off-track head scanning on linear tracks: possible implications for representational and dynamic properties of hippocampal place cells.

Neuropsychologia·2026
Same journal

Identifying networks within an fMRI multivariate searchlight analysis.

Neuropsychologia·2026
Same journal

Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

Neuropsychologia·2026
Same journal

Deficient processing of regularity violations during visuospatial neglect: a visual mismatch negativity study.

Neuropsychologia·2026
Same journal

Seeing is believing: mental imagery amplifies moral, emotional, and motivational responding to mentally constructed hypothetical events.

Neuropsychologia·2026
Same journal

From past recall to future projection: What does verb tense production reveal about mental time travel in Alzheimer's disease?

Neuropsychologia·2026
See all related articles

Frontal lobe damage impairs everyday behavior organization. Even with realistic virtual environments, patients with prefrontal cortex damage showed significant action execution deficits, suggesting planning defects impact action completion.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Frontal lobe lesions often cause significant behavioral organization problems.
  • Script generation tasks evaluate the ability to plan and structure actions.
  • Understanding the link between conceptual action knowledge and execution is crucial.

Purpose of the Study:

  • To investigate how neuropsychological deficits in action knowledge formulation affect action execution.
  • To compare action execution in patients with prefrontal cortex damage versus healthy individuals.
  • To determine the impact of a realistic context on action planning and execution.

Main Methods:

  • Examined seven patients with prefrontal cortex damage and sixteen healthy subjects.
  • Subjects verbally formulated action plans and then executed them in a 3D virtual apartment.

Related Experiment Videos

  • Assessed performance, action slips, omissions, initiation failures, and planning time.

    • Main Results:

    • A realistic virtual context improved patient performance but did not eliminate specific execution impairments.
    • Patients exhibited action slips, omissions, initiation failures, and purposeless movements.
    • Unlike controls, patients did not spend more time on plan execution than generation.

    Conclusions:

    • Defective routine plan formulation following frontal lobe lesions can impair subsequent action execution.
    • Prefrontal cortex damage leads to specific deficits in the real-time execution of planned actions.
    • The findings highlight the critical role of the frontal lobe in both planning and executing complex behaviors.