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Updated: Jul 23, 2026

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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
Published on: January 27, 2019
Short report: Hyperammonaemia in critically ill septic infants
P McEwan1, D Simpson, J M Kirk
1Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
Archives of Disease in Childhood
|May 23, 2001
Abstract:
Three infants with subphrenic abscess, pyonephrosis, and obstructive ureterocoele respectively had grossly increased concentrations of plasma ammonia. This was considered to be a result of infections with urea splitting organisms. All died in spite of intensive care support, including specific measures to reduce plasma ammonia.

