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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Steroid-associated osteonecrosis of the knee: a comprehensive review
K Low1, M A Mont, D S Hungerford
1Department of Orthopaedics, John Hopkins Medical Institution, Baltimore, Maryland, USA.
Instructional Course Lectures
|May 25, 2001
Abstract:
Steroid-associated osteonecrosis of the knee is a disease of young patients (generally younger than 45 years old) who often have underlying immunocompromising disorders. Although many theories have been postulated, the exact pathophysiology of the disorder is still unknown. Precollapse lesions can be treated with core decompression for prolonged symptomatic relief. Later-stage lesions are treated with total knee replacements, which have less than optimal results reported to date.
