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Benign metastasizing leiomyoma: clinical, imaging, and pathologic correlation.
S Abramson1, R C Gilkeson, J D Goldstein
1Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Ave., Cleveland, OH 44106, USA.
AJR. American Journal of Roentgenology
|May 25, 2001
Summary
Benign metastasizing leiomyoma is an asymptomatic condition. This rare disease presents as numerous, well-defined pulmonary lesions on imaging, without a specific distribution pattern.
Area of Science:
- Reproductive medicine
- Oncology
- Radiology
Background:
- Benign metastasizing leiomyoma (BML) is a rare condition where leiomyoma cells spread outside the uterus.
- BML typically affects women of reproductive age and is often associated with estrogen exposure.
Purpose of the Study:
- To detail the clinical presentation of BML.
- To describe the characteristic radiographic and computed tomography (CT) findings in patients with BML.
Main Methods:
- Review of clinical cases diagnosed with BML.
- Analysis of imaging data, including plain radiography and CT scans.
- Correlation of imaging findings with clinical presentation.
Main Results:
- BML is generally asymptomatic.
- Imaging reveals numerous, well-defined pulmonary nodules.
- Lesions show no preferential distribution within the lungs.
Conclusions:
- BML is a rare, asymptomatic pulmonary disease.
- Characteristic imaging findings include multiple, discrete lung nodules.
- Diagnosis relies on integrating clinical and radiological data.