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Related Experiment Videos

Gastric tonometry: where do we stand?

M A Hamilton1, M G Mythen

  • 1Center for Anesthesia, Middlesex Hospital, and Center for Anesthesia, University College, London, UK.

Current Opinion in Critical Care
|May 25, 2001
PubMed
Summary
This summary is machine-generated.

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Gastric tonometry is a sensitive predictor of outcomes in critically ill patients, identifying those who benefit from interventions. However, therapies to normalize gastric mucosal pH have shown limited success, highlighting the need for further research.

Area of Science:

  • Critical Care Medicine
  • Gastroenterology
  • Physiology

Background:

  • Gastric tonometry is a sensitive, though not specific, predictor of outcomes in critically ill patients.
  • Patients maintaining a normal gastric mucosal pH generally have better outcomes.
  • Therapies targeting abnormal gastric mucosal pH have had limited success.

Purpose of the Study:

  • To review the utility of gastric tonometry in critically ill patients.
  • To evaluate the effectiveness of interventions aimed at improving gastric mucosal pH.
  • To discuss the evolution of gastric tonometry methodology and indices.

Main Methods:

  • Review of existing literature on gastric tonometry in critical care.
  • Analysis of interventional trials using gastric mucosal pH.

Related Experiment Videos

  • Discussion of newer indices like PCO2 (PgCO2) and their validation.

    • Main Results:

    • A trend toward benefit in protocol groups of interventional trials was observed, despite generally negative reports.
    • Gastric tonometry appears to identify patient 'responders' and 'nonresponders' to therapy.
    • Newer indices of gut perfusion require further validation as outcome predictors.

    Conclusions:

    • Gastric tonometry is valuable for identifying patient response to critical care interventions.
    • Further research is needed to understand gastrointestinal physiology and the clinical utility of gas tonometry.
    • Prospective, randomized controlled trials are necessary to establish gas tonometry as a routine tool for guiding therapy.