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[Opportunistic infections. Developments and trends since establishment of HAART therapy]
1Med. Klinik am Klinikum Salzgitter.
Since the middle of the nineteen-nineties, the number of opportunistic infections has been on the decrease. For the most part, this is due to HAART and optimized primary and secondary prophylactic measures. Nevertheless, these infections have not lost any of their clinical relevance, for example, in patients in whom they are index conditions for the HIV diagnosis, or in whom immune reconstitution under HAART fails. New therapeutic concepts that improve the patients chances of surviving have been developed. On the basis of current results it is now recommended that secondary prophylaxis be forgone when under HAART the CD4 cell count increases to above 200/microL.
Since the middle of the nineteen-nineties, the number of opportunistic infections has been on the decrease. For the most part, this is due to HAART and optimized primary and secondary prophylactic measures. Nevertheless, these infections have not lost any of their clinical relevance, for example, in patients in whom they are index conditions for the HIV diagnosis, or in whom immune reconstitution under HAART fails. New therapeutic concepts that improve the patients chances of surviving have been developed. On the basis of current results it is now recommended that secondary prophylaxis be forgone when under HAART the CD4 cell count increases to above 200/microL.