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Updated: Jul 25, 2026

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High-throughput Physical Mapping of Chromosomes using Automated in situ Hybridization
Published on: June 28, 2012
Paramecium genome survey: a pilot project
P Dessen1, M Zagulski, R Gromadka
1Service de Bioinformatique, UMS825 CNRS/SC13 INSERM, 7 rue Guy Môquet BP8, 94801 Villejuif Cedex, France.
Trends in Genetics : TIG
|May 30, 2001
Abstract:
A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

